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Midazolam
Essential medicine status
General description
Midazolam is a benzodiazepine with a wide range of effects including anxiolytic, sedative, muscle relaxant, antiepileptic and anterograde amnesic.
INN
Midazolam
Medicine type
Chemical agent
EML status history
First added in 2009 (TRS 958) for Palliative care
Added in 2015 (TRS 994) for Status epilepticus
Therapeutic equivalent for
Wikipedia
DrugBank
Recommendations
Section
Preoperative medication and sedation for short-term procedures
  • Parenteral > General injections > IV: 1 mg per mL
  • Oral > Liquid: 2 mg per mL
  • Oral > Solid: 15 mg tablet; 7.5 mg tablet
Section
Medicines for other common symptoms in palliative care
  • Oral > Liquid: 2 mg per mL oral liquid
  • Oral > Solid: 7.5 mg solid oral dosage form; 15 mg solid oral dosage form
  • Parenteral > General injections > unspecified: 1 mg per mL injection; 5 mg per mL injection
Indications
Section
Anticonvulsants/antiepileptics
  • Parenteral > General injections > unspecified: 1 mg per mL in ampoule (for buccal administration); 10 mg per mL in ampoule (for buccal administration)
  • Local > Buccal > Solution: 5 mg per mL solution for oromucosal administration; 10 mg per mL solution for oromucosal administration