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Valproic acid
Essential medicine status
General description

INN
Valproic acid
Medicine type
Chemical agent
EML status history
First added in 1979 (TRS 641) for Epilepsy or seizures
Added in 2015 (TRS 994) for Status epilepticus
Therapeutic equivalent for
Wikipedia
Recommendations
Section
Anticonvulsants/antiepileptics
  • Oral > Liquid: 200 mg per 5 mL (sodium valproate)
  • Oral > Solid: 200 mg (sodium valproate) enteric-coated tablet; 500 mg (sodium valproate) enteric-coated tablet; 100 mg (sodium valproate) crushable tablet
  • Parenteral > General injections > IV: 100 mg per mL in 4 mL ampoule (sodium valproate); 100 mg per mL in 10 mL ampoule (sodium valproate)
Section
Medicines used in bipolar disorders
  • Oral > Solid: 200 mg enteric-coated (sodium valproate); 500 mg enteric-coated (sodium valproate)