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Valproic acid (sodium valproate)
Essential medicine status
General description

INN
Valproic acid
ATC codes
Medicine type
Chemical agent
EML status history
First added in 1979 (TRS 641) for Epilepsy or seizures
Added in 2015 (TRS 994) for Status epilepticus
Recommendations
Section
Anticonvulsants/antiepileptics
  • Oral > Liquid: 200 mg per 5 mL
  • Oral > Solid: 200 mg tablet (enteric-coated); 500 mg tablet (enteric-coated); 100 mg tablet (crushable)
  • Parenteral > General injections > IV: 100 mg per mL in 4 mL ampoule; 100 mg per mL in 10 mL ampoule
Section
Medicines used in bipolar disorders
  • Oral > Solid: 200 mg tablet (enteric-coated); 500 mg tablet (enteric-coated)