General description
Calcium folinate (also known as leucovorin, folinic acid) is a folic acid derivative that acts as a modulating and rescue agent in cancer chemotherapy protocols.
INN
Calcium folinate
ATC codes
Medicine type
Chemical agent
EML status history
First added in 1979
(TRS
641)
for
Malignant neoplasms of colon
Changed in 1979
(TRS
641)
for
Osteosarcoma of bone or articular cartilage of unspecified sites
Changed in 1979
(TRS
641)
for
Burkitt lymphoma including Burkitt leukaemia
Changed in 1979
(TRS
641)
for
Malignant neoplasm metastasis in large intestine
Changed in 1979
(TRS
641)
for
Malignant neoplasms of rectum
Changed in 1979
(TRS
641)
for
Malignant trophoblastic neoplasms of placenta
Changed in 1979
(TRS
641)
for
Unspecified malignant neoplasms of unspecified sites
Removed in 2015
(TRS
994)
for
Unspecified malignant neoplasms of unspecified sites
Wikipedia
DrugBank
Recommendations
Section
Cytotoxic medicines
- Parenteral > General injections > unspecified: 10 mg per mL in 5 mL ampoule; 7.5 mg per mL in 2 mL ampoule; 3 mg per mL in 10 mL ampoule
- Oral > Solid > tablet: 25 mg; 5 mg; 15 mg
- Parenteral > General injections > unspecified: 3 mg per mL in 10 mL ampoule; 7.5 mg per mL in 2 mL ampoule; 10 mg per mL in 5 mL ampoule
- Oral > Solid > tablet: 25 mg; 15 mg; 5 mg
- Oral > Solid: 15 mg tablet
- Parenteral > General injections > unspecified: 3 mg per mL in 10 mL ampoule
Indications
Malignant neoplasms of colon
Osteosarcoma of bone or articular cartilage of unspecified sites
Burkitt lymphoma including Burkitt leukaemia
Malignant neoplasm metastasis in large intestine
Malignant neoplasms of rectum
Malignant trophoblastic neoplasms of placenta
Unspecified malignant neoplasms of unspecified sites