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ATC codes: J01DD04
EMLc
Indication
Endophthalmitis ICD11 code: 9C21
INN
Ceftriaxone
Medicine type
Chemical agent
Antibiotic groups
List type
Core (EML)
(EMLc)
Additional notes
Do not administer with calcium and avoid in infants with hyperbilirubinaemia.
Formulations
Parenteral > General injections > unspecified: 250 mg in vial powder for injection (as sodium salt) ; 1 g in vial powder for injection (as sodium salt) ; 2 g in vial powder for injection (as sodium salt) (EML) ; 500 mg in vial powder for injection (as sodium salt)
EML status history
First added in 2021 (TRS 1035)
Changed in 2023 (TRS 1049)
Sex
All
Age
Also recommended for children
Age restriction
> 41 weeks corrected gestational age
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
DrugBank
Expert Committee recommendation
Following the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended: - the addition of a new strength formulation of ceftriaxone (powder for injection: 500 mg (as sodium) in vial) to the EML and EMLc. - the addition of new strength formulations of IV vancomycin (500 mg, 1 g (as hydrochloride) on the EMLc.
EML recommendations: Endophthalmitis
First choice
Second choice
First choice
ceftazidime co-prescribed with vancomycin
ceftriaxone co-prescribed with vancomycin
Second choice