ATC codes: J01FF01
Necrotising fasciitis ICD11 code: 1B71.Z
Medicine type
Chemical agent
Antibiotic groups
List type
Core (EML)
Parenteral > General injections > IV: 150 mg per mL (as phosphate) ; 600 mg per 4 mL (as phosphate) (EML) ; 900 mg per 6 mL (as phosphate) (EML)
Oral > Liquid: 75 mg per 5 mL powder for oral liquid (as palmitate hydrochloride) (EMLc)
Oral > Solid: 150 mg (as hydrochloride)
EML status history
First added in 2021 (TRS 1035)
Changed in 2023 (TRS 1049)
Also recommended for children
Therapeutic alternatives
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Expert Committee recommendation
In consideration of the review of the age appropriateness of formulations of medicines on the EMLc, and the comparison report of the EML versus EMLc, the Expert Committee recommended changes to the EMLc for addition of new, age-appropriate formulations and strengths of existing essential medicines, deletion of unavailable or age-inappropriate formulations and strengths, and other listing modifications as proposed in the application. The Committee also endorsed the proposals for further review of the public health relevance and evidence for specific medicines for use in children for potential future consideration for inclusion on the EMLc. The Committee noted and welcomed the ongoing review being coordinated by the Secretariat for the remaining sections of the EMLc for consideration by the 2025 Expert Committee. As a result of the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended: - replacing the oral liquid formulation of clindamycin (oral liquid 75 mg/5 mL) with powder for oral liquid 75 mg/5 mL (as palmitate hydrochloride) on the EML and EMLc - the addition of a new strength formulation of ceftriaxone (powder for injection: 500 mg (as sodium) in vial) to the EML and EMLc. - the range of strengths of metronidazole tablets be replaced with reference to specific strengths on the EML and EMLc. - the addition of new strength formulations of IV vancomycin (500 mg, 1 g (as hydrochloride) on the EMLc.
EML recommendations: Necrotising fasciitis
First choice
Second choice
First choice
Second choice