Export

Essential medicine status
ATC codes: B05BC01
EMLc
Indication
Cerebral oedema ICD11 code: 8D50.1
INN
Mannitol hexanitrate
Medicine type
Chemical agent
List type
Core (EML)
Complementary (EMLc)
Formulations
Parenteral > General injections > IV: 10% solution ; 20% solution
EML status history
First added in 1977 (TRS 615)
Changed in 1979 (TRS 641)
Changed in 1987 (TRS 770)
Changed in 1991 (TRS 825)
Changed in 2003 (TRS 920)
Changed in 2007 (TRS 950)
Sex
All
Age
Also recommended for children
Therapeutic equivalence
The recommendation is for this specific medicine
Patent information
Patents have expired in most jurisdictions
Wikipedia
DrugBank
Summary of evidence and Expert Committee recommendations
The EMLc Subcommittee considered that diuretics were essential for use in children in the treatment of ascites, acute or chronic renal failure or acute glomerulonephritis. Nephrotic syndrome oedema responds poorly to diuresis and loop diuretics may be hazardous because patients are often volume depleted despite oedema. The Subcommittee endorsed the inclusion of mannitol on the EMLc but recommended it be listed on the complementary list of the EMLc and be reviewed at the next meeting in light of potential newer diuretic agents.