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Codes ATC: J01DD01
EMLc
Indication
Sepsis without septic shock Code ICD11: 1G40
INN
Cefotaxime
Type de médicament
Chemical agent
Groupes d'antibiotiques
Type de liste
Liste de base (EML)
(EMLc)
Additional notes
3rd generation cephalosporin of choice for use in hospitalized neonates.
Formulations
Parenteral > General injections > unspecified: 250 mg in vial powder for injection (as sodium salt) (EMLc) ; 500 mg in vial powder for injection (as sodium salt) (EMLc) ; 1 g in vial powder for injection (as sodium salt) (EMLc) ; 2 g in vial powder for injection (as sodium salt) (EMLc)
Historique des statuts LME
Ajouté pour la première fois en 2017 (TRS 1006)
Modifié en 2023 (TRS 1049)
Sexe
Tous
Âge
Enfants (1 mois - 12 ans)
Équivalence thérapeutique
La recommandation concerne ce médicament spécifique
Renseignements sur le brevet
Patents have expired in most jurisdictions
Lire la suite sur les brevets.
Wikipédia
DrugBank
Recommandation du comité d'experts
In consideration of the review of the age appropriateness of formulations of medicines on the EMLc, and the comparison report of the EML versus EMLc, the Expert Committee recommended changes to the EMLc for addition of new, age-appropriate formulations and strengths of existing essential medicines, deletion of unavailable or age-inappropriate formulations and strengths, and other listing modifications as proposed in the application. The Committee also endorsed the proposals for further review of the public health relevance and evidence for specific medicines for use in children for potential future consideration for inclusion on the EMLc. The Committee noted and welcomed the ongoing review being coordinated by the Secretariat for the remaining sections of the EMLc for consideration by the 2025 Expert Committee. As a result of the review of the age-appropriateness of formulations on the EMLc, the Expert Committee recommended: - the addition of a new strength formulation of amikacin (injection 50 mg/mL (as sulfate) in 2 mL vial) to the EMLc. - the addition of new formulations of amoxicillin (dispersible, scored tablet, 250 mg and 500 mg) to the EMLc. - the addition of new strength formulations of cefotaxime (powder for injection: 500 mg; 1 g; 2 g (as sodium) in vial) to the EML and EMLc. - the addition of a new strength formulation of ceftriaxone (powder for injection: 500 mg (as sodium) in vial) to the EML and EMLc. - the addition of new strength formulations of cloxacillin (capsule 250 mg, powder for injection 250 mg (as sodium) and powder for oral liquid 250 mg/5 mL (as sodium) on the EMLc.
Recommandations de la LME : Sepsis without septic shock
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